In the course of history, a remarkable name change has taken place because of the similarities between the clinical syndromes caused by dengue and chikungunya virus infections. All of these viruses can be transmitted by Aedes aegypti and Ae. The return of chikungunya virus to the Americas provides an opportunity to revisit the epidemiology of this zoonotic togavirus from Africa and to contrast it with that of dengue viruses, flaviviruses that are maintained as zoonoses in Southeast Asia. A total of 1,094,661 suspected and 26,606 laboratory-confirmed chikungunya cases have been reported ( ). Martin, in the Caribbean, in December 2013, and as of January 9, 2015, the US Centers for Disease Control and Prevention reported that the disease had been identified in 42 countries or territories in the Caribbean, Central America, South America, and North America. The return of this viral exanthem was first recognized on St. Chikungunya has returned to the Americas after an absence of ≈200 years.
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